DERIVATIVES OF IMIDAZOPYRIDINE STIMULATING NEUROGENESIS Russian patent published in 2018 - IPC C07D471/04 A61K31/437 A61P25/00 

Abstract RU 2644949 C2

FIELD: chemistry.

SUBSTANCE: invention refers to organic chemistry and specifically to novel imidazopyridine derivatives of formula I or to its pharmaceutically acceptable acid addition salt or its racemic mixture, Ar is phenyl or pyridinyl; X1 is N or CH; X2 is N or CH provided that only one of X1 or X2 is N and the other is CH; R1 is hydrogen, halogen, lower alkoxy, lower alkyl substituted with halogen, cyano or S(O)2-lower alkyl; R2 is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkyl substituted with halogen; and n is 1 or 2. Invention also relates to the pharmaceutical composition based on the compound of formula I and use thereof. (I).

EFFECT: new imidazopyridine derivatives stimulating neurogenesis have been obtained.

13 cl, 1 tbl, 24 ex

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RU 2 644 949 C2

Authors

Chekkarelli Simona M.

Dzhagasia Ravi

Yakob-Roetne Roland

Vikhmann Yurgen

Dates

2018-02-15Published

2013-11-26Filed