APTAMERS SPECIFIC TO EXTRACELLULAR GLYCOSYLATED DOMAIN OF THE HUMAN CD47 RECEPTOR Russian patent published in 2018 - IPC C12N15/115 C12Q1/68 

Abstract RU 2645457 C2

FIELD: biotechnology; medicine.

SUBSTANCE: invention relates to biotechnology and medicine. Aptamer specific for the extracellular glycosylated domain of the human CD47 receptor is proposed, which is capable of blocking its interaction with the natural SIRP-alpha ligand.

EFFECT: present invention can find further application in therapy.

1 cl, 4 dwg

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RU 2 645 457 C2

Authors

Chumakov Stepan Petrovich

Kravchenko Yuliya Evgenevna

Lezhnin Yurij Nikolaevich

Frolova Elena Ivanovna

Dates

2018-02-21Published

2016-07-05Filed