METHOD FOR SILVER PROTEINATE PRODUCTION Russian patent published in 2018 - IPC A61K38/17 A61K33/38 C07K14/435 B01J19/08 C01G5/00 

FIELD: pharmacology.

SUBSTANCE: method for silver proteinate production is proposed. A protein hydrolyzate solution and a silver salt solution are prepared in distilled water. The silver salt solution is added to the protein hydrolyzate solution in terms of final silver concentration of not more than 3 wt % and at a silver/protein hydrolyzate weight ratio of 1/5-1/20, the resulting solution is mixed and poured into a flat container until a layer of no more than 5 cm thick is formed. The layer is subjected to electron-beam processing by passing a beam of accelerated electrons through it in an absorbed dose of 5-30 kGy. As protein hydrolyzate, hydrolysates of gelatine, casein, albumin are used, as a water-soluble silver salt - silver nitrate, silver acetate.

EFFECT: invention allows to increase the stability and safety of the antimicrobial activity of the aqueous solution of silver proteinate and to release it in the form of a ready-to-use dosage form with a long shelf life without drying and subsequent extemporal dissolution of the preparation.

4 cl, 1 dwg, 1 tbl, 10 ex