FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine, in particular to obstetrics, gynecology, reproductology and immunology, and is intended to predict the in vitro fertilization (IVF) program effectiveness. Macrophage-colony-stimulating factor level in peripheral venous blood is determined by the enzyme immunoassay before the superovulation stimulation begins, in leukocytes is by its receptor gene polymorphism. Depending on the macrophage-colony-stimulating factor serum level and its receptor gene polymorphic variants rs386693509, rs3216780 3'UTR gene region predicting the likelihood of pregnancy.
EFFECT: invention provides an increase in the sensitivity and accuracy of predicting the onset of pregnancy in the IVF program.
1 cl, 1 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION OF THE OCCASION OF CLINICAL PREGNANCY IN IVF CYCLES IN PATIENTS WITH A PREDICTION OF SUBOPTIMALE RESPONSE TO CONTROLLED OVARIAN STIMULATION | 2022 |
|
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|
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| METHOD FOR PREDICTION OF RISK OF EARLY FETAL LOSS IN IVF INDUCED PREGNANCIES | 2009 |
|
RU2394495C1 |
| METHOD FOR CLINICAL PREGNANCY PROBABILITY PREDICTION FOR WOMEN WITH A BODY MASS INDEX OF 18,5 TO 28,49 IN VITRO FERTILIZATION PROGRAMME BASED ON ASSESSMENT OF LEPTIN LEVEL IN BLOOD PLASMA AND MITOCHONDRIA TRANSMEMBRANE POTENTIAL IN PERIPHERAL BLOOD MONONUCLEAR CELLS | 2016 |
|
RU2614725C1 |
| METHOD FOR PREDICTION OF ONSET OF PREGNANCY IN FEMALES WITH TUBAL-PERITONEAL INFERTILITY IN IN VITRO FERTILISATION PROGRAMME | 2013 |
|
RU2523401C1 |
| METHOD FOR PREDICTION OF CLINICAL OUTCOME OF EXTRACORPOREAL FERTILISATION AND EMBRYO TRANSFER | 2011 |
|
RU2474822C1 |
| METHOD FOR EMBRYO QUALITY PREDICTION IN EXTRACORPOREAL FERTILISATION IN INFERTILE WOMEN | 2010 |
|
RU2441243C1 |
| METHOD FOR PREDICTION OF EMBRYO ANEUPLOIDY IN THE EXTRACORPORAL FERTILIZATION PROGRAM IN WOMEN WITH ENDOMETRIOSIS-ASSOCIATED INFERTILITY | 2020 |
|
RU2752783C1 |
| PREDICTION METHOD OF OUTCOMES OF INFERTILITY TREATMENT BY EXTRACORPORAL IMPREGNATION METHOD | 2007 |
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RU2357673C1 |
