COMBINATION OF COMPONENTS FOR PREVENTION AND TREATMENT OF INDISPOSITION Russian patent published in 2018 - IPC A61K31/14 A61K31/715 A61K31/202 A61K31/44 A61K31/714 A61K31/4985 A61K31/685 A61K31/688 A61K31/375 A61K31/355 A61K33/04 A61P25/28 A23L29/00 

FIELD: medicine; pharmacology.

SUBSTANCE: use of the composition, which comprises the following items, is proposed (i) the nucleoside analog, which is selected from the group of uridine, deoxyuridine, uridine phosphates (UMP, dUMP, UDP, UTP), uracil and acylated derivatives of uridine, (ii) ω-3 polyunsaturated fatty acid, which is selected from the group DHA, DPA and EPA, (iii) vitamin B, which is selected from the group of vitamin B6, vitamin B12 and vitamin B9, (iv) phosphatidylcholine, (v) the antioxidant, which is selected from the group of vitamin C, vitamin E and selenium, and (vi) choline, provided that the weight ratio of phosphatidylcholine to choline is more than 0.1, for the prevention or treatment of indisposition of the patient with simultaneous increase or maintenance of the body mass index of the patient without the necessity to increase the calorie intake, where the composition is intended for administration to the person, who suffers from the disorder, which is selected from the group: dementia and Alzheimer's disease, where such a person has the body mass index (BMI) of less than 26, and where the indisposition is determined according to the compliance with at least two criteria, which are selected from the group: muscle weakness, feelings of excessive defatigation or fatigue, abnormally low physical activity, slow or unstable gait, weight loss and neurological dysfunction; the application of the mentioned composition for the above mentioned purposes (3 options); the nutritional composition for its use as described above.

EFFECT: technical result is the increased BMI and the implementation of the stated purposes.

25 cl, 2 dwg, 10 tbl, 12 ex