FIELD: pharmacology.
SUBSTANCE: invention is a composition for antitumour therapy comprising bendamustine; the first charged cyclopolysaccharide having at least one charged anionic group selected from sulfate and sulfonyl, in particular a sulfobutyl ether of beta-cyclodextrin; and a stabilizing agent which is the second cyclopolysaccharide having at least one group selected from amine, guanidine and quaternary ammonium, in particular heptakis(6-amino-6-deoxy)beta cyclodextrin.
EFFECT: composition has unexpectedly high stability under conditions of reactive-active environment, for example in plasma, in combination with unexpectedly high antitumour activity.
9 cl, 2 tbl, 3 ex
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