FIELD: medicine.
SUBSTANCE: discloses an injectable pharmaceutical composition for the treatment of a pathological condition of the liver, containing: (a) 25 mg/ml of ursodeoxycholic acid and (b) from 179 mg/ml to 248 mg/ml of sulfobutyl ether -β -cyclodextrin (variants).
EFFECT: providing a composition based on ursodeoxycholic acid suitable for intravenous administration, which is stable under environmental and/or cooling conditions, characterized by a significantly reduced volume for intravenous administration, and providing completely dissolved ursodeoxycholic acid without the need to use large amounts of strong bases.
5 cl, 3 tbl, 4 ex
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Authors
Dates
2023-10-13—Published
2020-11-19—Filed