FIELD: pharmacology.
SUBSTANCE: antioxidant complex of the invention represents a complex of carnosine with α-lipoic acid, obtained by mixing of α-lipoic acid with an aqueous solution of carnosine in an equimolar ratio. Application of the invention relates to the use of the said antioxidant complex for protection of mammals against oxidative stress.
EFFECT: application of inventions allows to obtain a water-soluble complex stable at physiological conditions, with increased efficiency and greater resistance to hydrolysis by serum carnosinase compared to its components.
4 cl, 3 dwg, 2 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| AGENT POSSESSING ANTIAGGREGANT, CYTOPROTECTIVE AND ANTIOXIDANT ACTIVITY | 2018 |
|
RU2694061C1 |
| AGENT SHOWING ANTIHYPOXIC AND ANTIOXIDANT ACTIVITY | 2001 |
|
RU2191592C1 |
| USE OF L-CARNOSINE FOR PRODUCING NANOPREPARATION POSSESSING ANTIHYPOXIC AND ANTIOXIDANT ACTIVITY | 2012 |
|
RU2482867C1 |
| REMEDY WITH ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITY | 2021 |
|
RU2777391C1 |
| DRUG POSSESSING ANTIHYPOXIC, ACTOPROTECTIVE, NOOTROPIC ACTIVITIES AND HAVING EFFECT ON PHYSICAL EFFICIENCY, AND BASED PHARMACEUTICAL COMPOSITION | 2011 |
|
RU2462245C1 |
| METHOD FOR PREVENTING AND CORRECTING METABOLIC AND FUNCTIONAL DISORDERS OF THE CENTRAL NERVOUS SYSTEM UNDER STRESS CONDITIONS | 2019 |
|
RU2717107C1 |
| AGENT WITH NEUROPROTECTIVE ANTI-ISCHEMIC ACTIVITY | 2022 |
|
RU2780112C1 |
| AGENT FOR DISEASES ASSOCIATED WITH STRESS-RELATED CONDITIONS IN DISEASES AND DISORDERS IN HUMAN AND ANIMALS, AND ALSO METHOD OF TREATING AND/OR PREVENTING WITH USING SUCH AGENT | 2009 |
|
RU2450823C2 |
| METHOD FOR CORRECTION OF CARBOHYDRATE-PROTEIN METABOLIC DISTURBANCE IN PANCREATIC CONNECTIVE TISSUE IN EXPERIMENTAL PRENATAL ALCOHOLIC INTOXICATION | 2011 |
|
RU2472230C2 |
| NOVEL GLYPROLINS WITH NOOTROPIC, ANTI-HYPOXIC, NEUROPROTECTIVE AND ANSSIYLITIS ACTIVITY | 2016 |
|
RU2646604C2 |
