FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry, namely to an antibody specifically binding a conformationally dependent epitope of an amino acid sequence of the N-WFDC domain of the HE4a polypeptide, as well as to the kit containing it. Also disclosed is a method for screening the presence of ovarian cancer in a subject or diagnosing an ovarian cancer in an individual using an antibody, which specifically binds a conformationally dependent epitope in the amino acid sequence of the N-WFDC domain of the HE 4a polypeptide.
EFFECT: invention allows to effectively diagnose ovarian cancer in a subject.
10 cl, 12 dwg, 3 tbl, 7 ex
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