FIELD: chemistry.
SUBSTANCE: invention relates to novel compounds in the series of 1,2,3-substituted benzimidazolium salts, namely 1,2,3-tri and 1,2,3,5-substituted benzimidazolium bromides of general formula I
I a,b.
EFFECT: novel compounds with inhibitory properties for protein-tyrosine phosphatase 1B type (PTP1B), which can be used for the control of PTP1B-mediated diseases, have been obtained.
4 cl, 3 ex, 1 tbl, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIDIABETIC REMEDY | 2017 |
|
RU2657832C1 |
| 1-SUBSTITUTED-3-{[2-(3,5-DI-TRET-4-HYDROXYPHENYL)-2-OXOETHYL]}-2AMINOBENZIMIDAZOLIUM BROMIDES WITH ANTIPLATELET AND ANTIOXIDANT PROPERTIES | 2016 |
|
RU2623439C1 |
| 9-SUBSTITUTED-2-BIPHENYLIMIDAZO[1,2-A]BENZIMIDAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, HAVING ANTIOXIDANT AND ANTIRADICAL PROPERTIES | 2017 |
|
RU2649979C1 |
| 9-BENZYL-2-BIPHENYLIMIDAZO[1,2-A]BENZIMIDAZOLE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF THAT EXPRESS PROPERTIES OF DESTROYERS OF TRANSVERSAL CROSS-LINKS OF GLYCOSYLATED PROTEINS | 2016 |
|
RU2627769C1 |
| 2'-AMINO-2,5'-DIOXO-5-PHENYL-1,2,5',6',7',8'-HEXAHYDRO-1'H-SPIRO[PYRROL-3,4'-QUINOLINES] | 2020 |
|
RU2743922C1 |
| METHOD OF PRODUCING β-KETOSULPHONES AND 1,4-DIKETONES | 2011 |
|
RU2455271C1 |
| METHOD FOR PRODUCING PYRROLO[2,1-A]ISOQUINOLINES | 2017 |
|
RU2656225C1 |
| METHOD OF PRODUCING INDOLIZINO[7,6-b]INDOLE DERIVATIVES | 2010 |
|
RU2439073C1 |
| 2-(CHROMENO[4,3-D]PYRIMIDIN-5-YL)ACETIC ACID DERIVATIVES AND A METHOD FOR PRODUCTION THEREOF | 2019 |
|
RU2716597C1 |
| METHOD OF PRODUCING BIS(5-ALKYL-2-FURYL)(2-AZIDOPHENYL)METHANE DERIVATIVES | 2012 |
|
RU2502735C1 |
