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IPC

C07D235/06(2006-01-01)

C07D235/30(2006-01-01)

A61K31/4184(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2018102470, 2018-01-22

(24)

Start date

2018-01-22

(22)

Actual filing date

2018-01-22

(45)

Published

2018-04-25

(72)

Inventor

Zhukovskaya Olga NikolaevnaSpasov Aleksandr AlekseevichBabkov Denis AleksandrovichMorkovnik Anatolij SavelevichBrigadirova Anastasiya Andreevna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Federalnyj Universitet"Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

BROMIDES OF BENZIMIDAZOLIUM DERIVATIVES AS INHIBITORS OF PROTEIN-TYROSINEPHOSPHATASE 1B TYPE (PTP1B) Russian patent published in 2018 - IPC C07D235/06 C07D235/30 A61K31/4184 A61P35/00

Abstract RU 2652112 C1

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds in the series of 1,2,3-substituted benzimidazolium salts, namely 1,2,3-tri and 1,2,3,5-substituted benzimidazolium bromides of general formula I

I a,b.

EFFECT: novel compounds with inhibitory properties for protein-tyrosine phosphatase 1B type (PTP1B), which can be used for the control of PTP1B-mediated diseases, have been obtained.

4 cl, 3 ex, 1 tbl, 1 dwg

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RU 2 652 112 C1

Authors

Zhukovskaya Olga Nikolaevna

Spasov Aleksandr Alekseevich

Babkov Denis Aleksandrovich

Morkovnik Anatolij Savelevich

Brigadirova Anastasiya Andreevna

Dates

2018-04-25—Published

2018-01-22—Filed