FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing bis(5-alkyl-2-furyl)(2-azidophenyl)methane derivatives of general formula I, which can be used as starting compounds in synthesis of indoles, promising biologically active substances. A mixture of readily available 2-azidobenzaldehydes and 2-alkylfurans is treated with acids in different solvents:
EFFECT: method enables to obtain a compound of formula I with high output.
2 tbl, 5 ex
Title | Year | Author | Number |
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METHOD OF PRODUCING 2-(2-ACYLVINYL)INDOLES | 2012 |
|
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RU2488581C1 |
METHOD OF PRODUCING 3-(2-FURYL) PHTHALIDE DERIVATIVES | 2015 |
|
RU2583058C1 |
METHOD FOR SYNTHESIS OF 4-(1H-INDOL-3-YL)-BUT-3-EN-2-ONE DERIVATIVES | 2009 |
|
RU2409564C1 |
METHOD OF OBTAINING DERIVATIVES OF N-ACETYL-4-HYDROXY-2METHYL-5-(5-METHYLFUR-2-YL)-1H-BENZO[g]INDOLE | 2008 |
|
RU2368611C9 |
PRODUCTION METHOD OF (E)-4-(INDOL-2-YL)PROP-2-EN-1-ONE DERIVATIVES | 2016 |
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RU2633999C1 |
METHOD FOR OBTAINING DERIVATIVES OF 2-(2-ACYLVINYL)INDOLES | 2014 |
|
RU2570421C1 |
Authors
Dates
2013-12-27—Published
2012-08-01—Filed