FIELD: pharmaceuticals.
SUBSTANCE: invention relates to the pharmaceutical industry and is a composition effective to enhance energy metabolism comprising at least 0.05 mg of a phosphodiesterase 5 (PDE 5) inhibitor and at least 500 mg leucine and/or at least 200 mg leucine metabolite, wherein the PDE 5 inhibitor contains sildenafil and wherein said leucine metabolite is selected from the group consisting of beta-hydroxymethyl butyrate (HMB), keto-isocaproic acid (KIC), and α-hydroxyisocaproic acid.
EFFECT: invention provides effective enhancement of regulation of energy metabolism, consisting in a synergistic increase in the oxidation of fatty acids in adipocytes and the utilisation of glucose.
24 cl, 27 dwg, 10 tbl, 5 ex
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