METHOD FOR DETERMINING AND DETECTING ANTIRETROVIRAL COMBINED DRUGS IN URINE Russian patent published in 2018 - IPC G01N1/28 G01N30/90 

Abstract RU 2655804 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine. Method for determining and detecting abacavir, lamivudine, zidovudine and stavudine in combinations in urine by chromatography in a thin layer of a sorbent of a solution of detectable substances and standard samples of witness substances is characterized by the fact that the test solution is prepared by isolating the detectable substances from urine with chloroform and a saturated solution of ammonium sulfate at pH 8.0, chromatography in a thin layer of sorbent is carried out on the plates "Sorbphil" in a solvent system of ethyl acetate-dichloromethane-25 % ammonia solution in a ratio of 17:4:1 and detecting zones of substances on a chromatogram in UV light.

EFFECT: invention can be used in chemical-toxicological and control-analytical laboratories for separation, identification and analysis of medicinal products.

1 cl, 1 ex

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RU 2 655 804 C1

Authors

Gonchikova Yuliya Anatolevna

Chmelevskaya Natalya Vladimirovna

Illarionova Elena Anatolevna

Tyzhigirova Valentina Viktorovna

Dates

2018-05-29Published

2017-04-11Filed