FIELD: medicine.
SUBSTANCE: invention relates to medicine. Method for determining and detecting abacavir, lamivudine, zidovudine and stavudine in combinations in urine by chromatography in a thin layer of a sorbent of a solution of detectable substances and standard samples of witness substances is characterized by the fact that the test solution is prepared by isolating the detectable substances from urine with chloroform and a saturated solution of ammonium sulfate at pH 8.0, chromatography in a thin layer of sorbent is carried out on the plates "Sorbphil" in a solvent system of ethyl acetate-dichloromethane-25 % ammonia solution in a ratio of 17:4:1 and detecting zones of substances on a chromatogram in UV light.
EFFECT: invention can be used in chemical-toxicological and control-analytical laboratories for separation, identification and analysis of medicinal products.
1 cl, 1 ex
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Authors
Dates
2018-05-29—Published
2017-04-11—Filed