METHOD FOR DETECTION IN URINE OF FLUORINE-CONTAINING DRUGS IN COMBINATIONS Russian patent published in 2019 - IPC G01N30/90 

Abstract RU 2710259 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used in chemical-toxicological and control-analytical laboratories for separation, identification and analysis of ofloxacin, linezolid and efavirenz in combinations. Method for detecting in urine ofloxacin, linezolid and efavirenz in combinations by chromatography in a thin layer of a sorbent of a solution of determined substances and standard samples of witness substances is characterized by the fact that a test solution is prepared by isolating the determined substances from urine with dichloromethane and a saturated solution of sodium chloride at pH 4.0, chromatography is carried out in a thin layer of the sorbent on plates "Sorbphil" in a system of solvents diethyl ether–- chloroform – 25 % ammonia solution at ratio of 15:2:1.5 and detection of zones of substances on a chromatogram in UV light.

EFFECT: disclosed is a method of detecting and detecting in urine ofloxacin, linezolid and efavirenz.

1 cl, 1 ex

Similar patents RU2710259C1

Title Year Author Number
METHOD FOR DETERMINING AND DETECTING ANTIRETROVIRAL COMBINED DRUGS IN URINE 2017
  • Gonchikova Yuliya Anatolevna
  • Chmelevskaya Natalya Vladimirovna
  • Illarionova Elena Anatolevna
  • Tyzhigirova Valentina Viktorovna
RU2655804C1
METHOD OF DETERMINING AND DETECTING HIV PROTEASE INHIBITORS IN BIOLOGICAL FLUIDS IN COMBINATIONS 2022
  • Mitina Anastasiya Eduardovna
  • Illarionova Elena Anatolevna
  • Chmelevskaya Natalya Vladimirovna
RU2800908C1
METHOD FOR ASSAY OF PHTHIVAZIDE AND METAZIDE PURITY 2001
  • Illarionova E.A.
  • Abramova L.V.
  • Illarionov A.I.
RU2225205C2
METHOD FOR ASSAY OF AUTHENTICITY AND PURITY OF XANTHINOL NICOTINATE 2002
  • Illarionova E.A.
  • Syrovatskij I.P.
  • Illarionov A.I.
RU2226274C2
METHOD OF DETERMINING N-(4-NITRO-2-PHENOXYPHENYL)-METHANESULPHONAMIDE IN BIOLOGICAL MATERIAL 2013
  • Shormanov Vladimir Kambulatovich
  • Gerasimov Dmitrij Aleksandrovich
  • Siplivaja Ljubov' Evgen'Evna
  • Siplivyj Gennadij Vjacheslavovich
  • Rynkevich Ekaterina Viktorovna
RU2537121C1
METHOD FOR PRODUCING SPIRAEOSIDE HAVING ANTIDEPRESSANT ACTIVITY 2020
  • Kurkin Vladimir Aleksandrovich
  • Sazanova Kseniya Nikolaevna
  • Sharipova Safiya Khakimovna
  • Zajtseva Elena Nikolaevna
  • Pravdivtseva Olga Evgenevna
RU2739191C1
METHOD FOR DETERMINATION OF O-(2,3-DIHYDRO-2,2-DIMETHYL-7-BENZOFURANYL)-N-METHYLCARBAMATE IN BIOLOGICAL SAMPLE 2004
  • Shormanov Vladimir Kambulatovich
  • Kovalenko Evgenij Anatol'Evich
  • Ivanov Vladimir Petrovich
  • Korolev Vladimir Anatol'Evich
  • Duritsyn Evgenij Petrovich
  • Pistunovich Elena Vladimirovna
RU2269780C1
METHOD OF DETERMINING 2,4-DICHLOROPHENOXY ACETIC ACID IN BIOLOGICAL MATERIAL 2011
  • Shormanov Vladimir Kambulatovich
  • Korolev Vladimir Anatol'Evich
  • Koropova Tat'Jana Fedorovna
  • Altukhova Anna Aleksandrovna
RU2453848C1
METHOD OF OBTAINING SUBSTANCE WITH DIURETIC AND ANTIDEPRESSANT ACTIVITY 2018
  • Kurkin Vladimir Aleksandrovich
  • Morozova Tatyana Vladimirovna
  • Pravdivtseva Olga Evgenevna
  • Zajtseva Elena Nikolaevna
  • Kurkina Anna Vladimirovna
RU2677284C1
METHOD OF DETERMINING 4-NITROPHENOL IN BIOLOGICAL MATERIAL 1994
  • Shormanov V.K.
  • Fursova I.A.
RU2121681C1

RU 2 710 259 C1

Authors

Tyutrina Vera Aleksandrovna

Illarionova Elena Anatolevna

Chmelevskaya Natalya Vladimirovna

Dates

2019-12-25Published

2019-06-26Filed