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2 656 595

(13)

(51)

IPC

C07F15/02(2006-01-01)

C07D487/22(2006-01-01)

A61K31/555(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2018109408, 2018-03-16

(24)

Start date

2018-03-16

(22)

Actual filing date

2018-03-16

(45)

Published

2018-06-06

(72)

Inventor

Nebolsin Vladimir EvgenevichZheltukhina Galina AleksandrovnaBlagodarov Sergej Valerevich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennostyu

CYCLIC HEMIN DERIVATIVE WITH ANTIMICROBIAL PROPERTIES AND METHOD FOR SYNTHESIS THEREOF Russian patent published in 2018 - IPC C07F15/02 C07D487/22 A61K31/555 A61P31/04

Abstract RU 2656595 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a novel hemin derivative, specifically a compound of formula (I)

where Meⁿ⁺ is Fe²⁺ or Fe³⁺; Hal^- is F^-, Cl^-, Br^- or I^-, or a pharmaceutically acceptable salt thereof. Also provided are a pharmaceutical composition, an antibacterial agent, an antiseptic, a disinfectant composition, methods for treating diseases caused by bacteria, and the use of a compound of formula (I).

EFFECT: proposed novel hemin derivative has antibacterial activity against a number of strains resistant to modern antibiotics.

28 cl, 3 dwg, 1 tbl, 4 ex

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RU 2 656 595 C1

Authors

Nebolsin Vladimir Evgenevich

Zheltukhina Galina Aleksandrovna

Blagodarov Sergej Valerevich

Dates

2018-06-06—Published

2018-03-16—Filed