FIELD: medicine.
SUBSTANCE: invention relates to medical diagnostics and discloses a method for early prognosis of risk of thromboembolic complications in patients suffering from coronary heart disease after myocardial revascularization by coronary artery bypass surgery (CABG). Method comprises determining the level of tumor necrosis factor-α (TNF-α), interleukin-10 (IL-10) and metalloproteinase-1 (MMP-1) in the blood serum using a solid-phase enzyme-linked immunosorbent assay, characterized in that if the IL-10 concentration is higher than 65 pg/ml in the preoperative period and higher than 320 pg/ml in the 1st day after operation, concentration of TNF-α is higher than 24 pg/ml in the preoperative period and MMP-1 concentration is higher 3.3 ng/ml in the preoperative and postoperative period, a high risk of thromboembolic complications after CABG surgery is predicted.
EFFECT: method allows in a short time after operation to predict the risk of thromboembolic complications and to adopt the necessary strategy for therapy of this disease state.
1 cl, 2 ex, 2 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREDICTING ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CHRONIC HEART FAILURE OF ISCHEMIC ETIOLOGY WITHIN A YEAR AFTER CORONARY ARTERY BYPASS GRAFTING | 2022 |
|
RU2801160C1 |
| METHOD FOR PREDICTING THE RISK OF THE UNFAVORABLE OUTCOME IN THE PATIENTS SUFFERING ISCHEMIC HEART DISEASE WITHIN THE YEAR FOLLOWING CORONARY ARTERIAL BYPASS | 2019 |
|
RU2704956C1 |
| METHOD OF EARLY PREDICTION OF POSTOPERATIVE COGNITIVE DYSFUNCTION IN IHD PATIENTS UNDERGOING CORONARY ARTERY BYPASS SURGERY | 2022 |
|
RU2795206C1 |
| METHOD FOR PREDICTION OF AN UNFAVORABLE OUTCOME IN PATIENTS WITH ISCHEMIC HEART DISEASE WHO UNDERWENT AORTOCORONARY BYPASS SURGERY | 2018 |
|
RU2688241C1 |
| METHOD OF PREDICTING THE RISK OF DEVELOPMENT OF COMPLICATIONS IN THE EARLY HOSPITAL PERIOD OF PATIENTS AFTER CORONARY SHUNTING IN THE CONDITIONS OF ARTIFICIAL CIRCULATION | 2017 |
|
RU2642238C1 |
| METHOD FOR INDUCTION OF EXTRACARDIAL MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH CORONARY HEART DISEASE | 2021 |
|
RU2758024C1 |
| METHOD OF PREPARING PATIENT SUFFERING FROM ISCHEMIC HEART DISEASE FOR CORONARY ARTERY BYPASS GRAFTING BY USING ARTIFICIAL BLOOD CIRCULATION APPARATUS | 2005 |
|
RU2304006C2 |
| METHOD FOR PREDICTION OF RISK OF UNFAVOURABLE CARDIOVASCULAR EVENTS IN PATIENTS SUFFERING ISCHEMIC HEART DISEASE WITH ISCHEMIC AND/OR POSTINFARCTION MYOCARDIAL DYSFUNCTION ACCOMPANYING CHRONIC CARDIAL INSUFFICIENCY | 2014 |
|
RU2568577C1 |
| METHOD OF ESTIMATING RISK OF DEVELOPMENT OF UNFAVOURABLE CARDIOVASCULAR EVENTS IN PATIENTS WITH ISCHEMIC HEART DISEASE SUBJECTED TO ENDOVASCULAR MYOCARDIUM REVASCULARISATION DURING ONE YEAR AFTER INTERFERENCE | 2010 |
|
RU2444297C1 |
| THERAPEUTIC APPROACH TO PATIENTS SUFFERING ISCHEMIA OF LOWER EXTREMITIES AND MULTIVESSEL DISEASE OF CORONARY BED | 2014 |
|
RU2553429C1 |
