FIELD: medicine.
SUBSTANCE: invention relates to ionizable lipids of formula I or their forms in the form of pharmaceutically acceptable salts, which can be useful for enhancing the delivery of therapeutic agents to patients. In formula I, n and m are independently 1, 2, 3, or 4; R1 and R2 are independently C10-18alkyl or C12-18alkenyl; when X is S, L is C1-4alkylene, -S-C1-4alkylene, -O-C1-4alkylene, -O-C(O)-C1-4alkylene, -S(O)2-C1-4alkylene or 
or when X is -CH2-, O or absent, L is -S-C1-4alkylene, -O-C(O)-C1-4alkylene, -S(O)2-C1-4alkylene or
. 
.
EFFECT: invention also relates to a pharmaceutical composition for enhancing the delivery of therapeutic agents comprising lipid compounds of formula I, a drug carrier comprising the composition, a pharmaceutical composition based on the drug carrier, and a method for delivering the drug.
45 cl, 4 dwg, 1 tbl, 24 ex
алкилен - alkylene
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