FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to biologically active peptides, and can be used in medicine. Based on the antimicrobial peptide tachyplezine from the hemocheto hemocyte, a representative of the family of beta-hairpin AMP, the peptide Tach1[Ile11Asp] was obtained.
EFFECT: invention allows to expand the range of peptide compounds having antitumor activity and low toxicity with respect to normal human cells.
1 cl, 4 dwg, 1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PEPTIDE EXHIBITING ANTIBACTERIAL AND ANTITUMOUR PROPERTIES | 2019 |
|
RU2702661C1 |
| pET-mChBac75Na PLASMID VECTOR, ESCHRICHIA COLI BL21(DE3/ pET-mChBac75Na BACTERIA STRAINS FOR CHBAC7NA MINIBACTENECIN ANTIMICROBIAL PEPTIDE EXPRESSION AND METHODS FOR PRODUCTION OF THESE PEPTIDES | 2016 |
|
RU2618850C2 |
| CATIONIC PEPTIDE EXHIBITING ANTIBACTERIAL PROPERTIES | 2021 |
|
RU2778856C1 |
| BETA-HAIRPIN POLYPEPTIDE WITH ANTIMICROBIAL ACTIVITY | 2015 |
|
RU2624020C2 |
| NIKOMYCIN PEPTIDE FROM NEREID NICOMACHE MINOR POSSESSING ANTIMICROBIAL AND ANTITUMOUR ACTIVITY | 2019 |
|
RU2721273C1 |
| PLASMID VECTOR pET-His8-TrxL-Acip1 STRAIN OF BACTERIA Escherichia coli BL21(DE3)/pET-His8-TrxL-Acip1 FOR EXPRESSION OF ANTIMICROBIAL PEPTIDE ACIPENSINA-1 AND METHOD OF PRODUCING SAID PEPTIDE | 2015 |
|
RU2580031C2 |
| BETA-HAIRPIN PEPTIDE WITH ANTIMICROBIAL ACTIVITY AGAINST MULTIDRUG-RESISTANT BACTERIA | 2023 |
|
RU2812977C1 |
| PLASMID VECTOR PET-PPSLTP, Escherichia coli BL21 (DE3) STAR/PET-PPSLTP BACTERIA STRAIN - PRODUCER OF PEA-BORNE ALLERGEN PIS S 3 AND METHOD FOR SAID ALLERGEN PRODUCTION | 2016 |
|
RU2618840C2 |
| RECOMBINANT PLASMID DNA pE-His8-TrxL-Ar2 ENCODING FUSION PROTEIN COMPRISING ANTIMICROBIAL SEA ANNELID WORM Arenicola marina PEPTIDE ARENICIN AND STRAIN Escherichia coli BL21(DE3)/pE-His8-TrxL-Ar2 AS PRODUCER OF ARENICIN-CONTAINING FUSION PROTEIN | 2006 |
|
RU2316590C1 |
| RECOMBINANT PLASMID DNA pЕ-Trx-Lc-def, Escherichia coli STRAIN FOR EXPRESSION OF ANTIMICROBIAL PEPTIDE OF LENTIL DEFENSIN Lens culinaris AND METHOD FOR PRODUCING SAID PEPTIDE | 2010 |
|
RU2456345C1 |
