PHARMACEUTICAL COMPOSITION AND APPLICATION OF PHOSPHOLIPID IN SUCH PHARMACEUTICAL COMPOSITION Russian patent published in 2018 - IPC A61K31/683 A61K31/192 A61K31/196 A61K47/44 A61K9/10 

Abstract RU 2659943 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to the pharmaceutical industry and is a pharmaceutical composition for use in humans and animals with at least one systemically and/or locally acting topically applied active ingredient and at least one phospholipid which contains at least phosphatidylcholine at a concentration of at least 60% by weight relative to the phospholipid, the phospholipid having a natural origin, the composition being of such a liquid consistency that it can be sprayed as droplets. According to the invention, the composition comprises such a phospholipid which improves the transport of the active ingredient through the cell membrane and which, in addition to at least 60% by weight of phosphatidylcholine, comprises an oil component in a concentration of 2% by weight to 4.8% by weight, wherein the oil component contains free fatty acids, sterols, mono- and diglycerides, triglycerides, tocopherol and/or fatty acid esters.

EFFECT: invention provides an improvement in the transport of the active ingredient through the cell membrane in topical application and a high penetration ability.

27 cl, 3 dwg, 2 tbl, 10 ex

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RU 2 659 943 C2

Authors

Bernd G. Zajgfrid

Dates

2018-07-04Published

2013-05-10Filed