FIELD: medicine.
SUBSTANCE: invention relates to medicine and pharmacy and is analgesic agent comprising substituted 2-[1-(1H-benzimidazol-2-yl)-3-phenyl-1H-1,2,4-triazol-5-yl]propanoic acid (I), selected from group: Ia – 2-[1-(1H-benzimidazol-2-yl)-3-(4-nitrophenyl)-1H-1,2,4-triazol-5-yl]propanoic acid; Ib – 2-[1-(1H-benzimidazol-2-yl)-3-(4-methoxyphenyl)-1H-1,2,4-triazol-5-yl]propanoic acid; Ic – 2-[1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1H-1,2,4-triazol-5-yl]propanoic acid; Id – 2-[1-(1H-benzimidazol-2-yl)-3-phenyl)-1H-1,2,4-triazol-5-yl]propanoic acid as the active substance.
EFFECT: implementation of invention allows to obtain low-toxicity analgesic agent that exhibits significantly greater analgesic activity than comparators commonly used in medicine.
1 cl, 4 ex, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANALGESING AND ANTIVIRAL AGENT BASED ON SUBSTITUTED 2-[1-(1H-BENZIMIDAZOL-2-YL)-3-PHENYL-1H-1,2,4-TRIAZOLE-5-YL]PROPANE ACID | 2018 |
|
RU2684781C1 |
| ANALGEZING AGENT ON THE BASIS OF SUBSTITUTED 2,2'-[(6-METHYLPYRIMIDIN-2,4-DYIL)BIS(3-PHENYL-1H-1,2,4-TRIAZOL-1,5-DIIL)]DIPROPANIC ACID | 2017 |
|
RU2676092C1 |
| ANALGESIC AND ANTIVIRAL AGENT BASED ON 2,2'-[(6-METHYLPYRIMIDINE-2,4-DIYL)BIS(3-(4-NITROPHENYL)-1H-1,2,4-TRIAZOLE-1,5-DIYL)]DIPROPANOIC ACID | 2017 |
|
RU2672878C1 |
| SUBSTITUTED 2-(1,3-BENZOTHIAZOL-2-YL)-3-PHENYL-1H-1,2,4-TRIAZOL-5-YL) PROPANOIC ACIDS AND SYNTHESIS METHOD THEREOF | 2015 |
|
RU2603958C1 |
| SUBSTITUTED 2-(1-(3-OXO-3,4-DIHYDROQUINOXALIN-2-YL)-3-PHENYL-1H-1,2,4-TRIAZOL-5-YL)PROPANOIC ACIDS AND METHOD FOR THEIR PRODUCTION | 2017 |
|
RU2645683C1 |
| 6-(2'-AMINO-2'-CARBOXYETHYLTHIO)-2-METHYLTHIO-4-PIVALOYLOXY-METHYL-1,2,4-TRIAZOLO[5,1-c] 1,2,4-TRIAZIN-7(4H)-ONE | 2011 |
|
RU2455304C1 |
| SUBSTITUTED 2,2'-[(6-METHYLPYRIMIDINE-2,4-DIYL)BIS(3-PHENYL-1N-1,2,4-TRIAZOL-1,5-DIYL)]DIPROPANIC ACIDS AND METHOD OF THEIR PRODUCTION | 2016 |
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| PHARMACEUTICAL COMPOSITION FOR CANCER AND VIRAL DISEASE TREATMENT, METHOD OF CANCER TREATMENT, METHOD OF VIRAL INFECTION TREATMENT BASED ON THEREOF | 1996 |
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| METHYL, CHLORO AND NITRO-DERIVATIVES OF N-{3, 5-DIOXO-4-AZATETRACYCLO [5.3.2.0.0]DODEC-11-EN-4-YL}-2-HYDROXYBENZAMIDE - ANTIVIRAL AGENTS INHIBITING REPLICATION OF DIFFERENT TYPES OF ORTHOPOXVIRUSES | 2010 |
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