METHOD FOR WATER-SOLUBLE COMPONENTS EXTRACTION FROM MARINE BROWN ALGAE ENRICHED BY FUCOIDAN AND IODINE Russian patent published in 2018 - IPC A61K36/03 B01D11/02 

FIELD: pharmacology.

SUBSTANCE: method for marine brown algae processing, including crushing of raw materials, homogenization of the mixture of raw materials a in solution, followed by extraction of water-soluble biologically active substances by filtration and drying, the raw material is pre-washed with water saturated with ozone, the raw material is homogenized in a solution that is water with calcium chloride at its concentration of 0.25 to 1% in the solution, additional grinding of the crushed algae is carried out in a mixture of raw materials in a solution at revolutions of rotary-pulse homogenizer, constituting 10 to 50% of the maximum engine revolutions, while 10 to 30% of the total amount of the mixture is loaded by batches during the preliminary homogenization, after completion of loading and preliminary homogenization, the rotation speed of the rotary-pulse homogenizer is increased and the mixture is homogenized for up to 5 hours at a mixture temperature of not more than 75°C. After homogenization, the homogenate is cryodestructed at a temperature from minus 18 to minus 20 degrees for 20-48 hours, for which the homogenate is placed in containers of 0.5 to 10 l, after cryodestruction, the frozen homogenate is thawed, after homogenate separation, liquid is separated from the precipitate, the precipitate is filtered under pressure and the resulting liquid is mixed with the liquid obtained in the previous step, the liquid phase is concentrated on a membrane cell, calcium chloride is removed, the precipitate and the liquid are dried.

EFFECT: above method promotes production of products with an increased content of biologically active substances.

5 cl, 2 tbl, 2 ex