PEPTIDE WITH NEUROPROTECTIVE ACTIVITY ON MODEL OF MFTP-INDUCED PARKINSONISM AND A PHARMACEUTICAL COMPOSITION ON ITS BASIS Russian patent published in 2018 - IPC C07K7/06 A61K38/08 A61P25/28 

Abstract RU 2662429 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to novel biologically active compounds, namely to peptides with neuroprotective and normalizing activity. Hexapeptide (1) of the formula Thr-Gly-Glu-Hse-His-Arg-NH2 as a neuroprotective and normalizing agent. New composition of a pharmaceutical composition based on a peptide containing hexapeptide (2.5 g/l) as active ingredient, a preservative in the form of nipagine (1.0 g/l), sodium chloride (10.0 g/l) and distilled water – the rest.

EFFECT: peptide has a high neuroprotective activity and can be used to produce a highly effective and non-toxic drug, which is used in the form of drops in the nose, and is intended for the prevention or treatment of Parkinson's disease.

2 cl, 3 dwg, 2 tbl, 3 ex

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RU 2 662 429 C1

Authors

Zolotarev Yurij Aleksandrovich

Dadayan Aleksandr Karenovich

Kozik Valerij Stanislavovich

Dates

2018-07-26Published

2017-08-01Filed