FIELD: medicine.
SUBSTANCE: present invention refers to medicine and can be used for early diagnosis of neurodegenerative diseases, particularly Parkinson's disease, at a pre-symptom (preclinical or prodromal) stage. Diagnostic technique is presented by a method in which an intranasal administration of alpha-methyl-p-tyrosine in the form of a hydrogel suitable for intranasal administration is carried out and a diagnosis of an early stage of Parkinson's disease is detected if observing the symptoms of motor disorders.
EFFECT: disclosed are a pharmaceutical composition based on alpha-methyl-p-tyrosine and a method for early diagnosis of Parkinson's disease.
2 cl, 4 ex, 3 dwg
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Authors
Dates
2020-04-21—Published
2019-02-01—Filed