ANIMAL MODELS OF CORNEA ANGIOGENESIS AND CORNEA ECTATIC STATES, METHODS FOR PRODUCTION THEREOF AND APPLICATION METHODS Russian patent published in 2018 - IPC A01N27/00 A01N31/08

Abstract RU 2662781 C2

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine, in particular to models of corneal diseases in animals. Methods are described for obtaining cornea angiogenesis models and ectatic cornea states, such as keratoconus, in an animal that is not a human, by applying an aromatic compound to the eye of a non-human animal. Cornea angiogenesis models and ectatic cornea states in non-human animals are also described, and methods for using the model in a non-human animal for screening compounds that modulate cornea angiogenesis and ectatic cornea states.

EFFECT: animal models of cornea angiogenesis and cornea ectatic states, methods of preparation thereof and methods of application are proposed.

25 cl, 7 dwg, 5 ex

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RU 2 662 781 C2

Authors

Solis Herrera, Arturo

Dates

2018-07-30—Published

2015-06-03—Filed