FIELD: biotechnology; medicine.
SUBSTANCE: method and a composition for enhancing the function of mitochondria in a subject's cell are proposed. Method comprises administering to the subject an effective amount of a composition comprising the isolated 5'-methylselenadenosine, selenadenosyl homocysteine, leucine-valine-selenomethionine-arginine, or combinations thereof. Said composition is administered in a dose providing the subject with 25 to 800 mcg of selenium per day. Effective amount enhances the mitochondrial function in the cell as compared to a cell not exposed to the composition.
EFFECT: inventions provide for enhancing the activity and function of mitochondria, for example in the skeletal muscle and liver of a subject, and are useful as a therapeutic and / or prophylactic agent for the treatment of diabetes, obesity and related conditions.
9 cl, 41 dwg, 8 tbl, 9 ex
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