FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a chemical-pharmaceutical industry and is a diagnostic preparation comprising a deuterated derivative of 2-amino-2-methylpropionic acid, and/or 2-(N-methylamino)-2-methylpropionic acid and/or a pharmaceutically acceptable salt thereof, or a mixture of at least two deuterated derivatives of 2-amino-2-methylpropionic acid and/or 2-(N-methylamino)-2-methylpropionic acid and/or a pharmaceutically acceptable salt thereof, for the diagnosis of cancerous diseases by magnetic resonance imaging and/or magnetic resonance spectroscopy on deuterium nuclei, as well as a method for diagnosing cancerous disease in a subject, comprising the steps of administering the diagnostic preparation to a subject, magnetic resonance imaging and/or magnetic resonance spectroscopy on deuterium nuclei after administering the diagnostic preparation and diagnosing the presence or absence of cancer on the basis of the observed signal strength of deuterium nuclei, reflecting the level of accumulation of the diagnostic preparation.
EFFECT: group of inventions allows producing a novel and effective diagnostic preparation that can be used for the diagnosis of cancerous diseases, in particular breast cancer, glioma, and also developing a novel effective and informative method for diagnosing cancer by magnetic resonance imaging and/or magnetic resonance spectroscopy on deuterium nuclei.
23 cl, 12 dwg, 3 ex
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