FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to a compound for producing a complex with a radionuclide label for diagnosing tumours expressing PSMA of general formula (I)
.
Also disclosed are a complex for diagnosing tumours and a pharmaceutical composition containing a compound of formula (I).
EFFECT: technical result is a novel compound for producing a complex with a radionuclide label for diagnosing tumours, characterized by solubility in aqueous solutions of not less than 18_5 mg/ml.
3 cl, 18 dwg, 3 tbl, 1 ex
Title | Year | Author | Number |
---|---|---|---|
PSMA-TARGET COMPOUND AND ITS COMPLEX WITH RADIONUCLIDES FOR THERANOSTICS OF TUMOR EXPRESSING PSMA | 2022 |
|
RU2803734C1 |
METHOD OF OBTAINING PSMA-TARGET COMPOUND COMPLEX BASED ON UREA Lu-PS-161 AND COMPLEX | 2023 |
|
RU2808636C1 |
PEPTIDE COMPOUND CAPABLE OF BINDING WITH PSMA, METHOD FOR PRODUCTION AND USE THEREOF | 2021 |
|
RU2823164C2 |
CONJUGATE OF A FLUORESCENT DYE WITH A PEPTIDE SUBSTANCE WHICH CONTAINS A PSMA-BINDING LIGAND BASED ON A UREA DERIVATIVE FOR VISUALIZING CELLS EXPRESSING PSMA, A METHOD FOR PRODUCTION THEREOF AND USE THEREOF | 2019 |
|
RU2713151C1 |
LYOPHILISATE BASED ON PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS FOR PREPARING A RADIOPHARMACEUTICAL COMPOSITION IN FORM OF SOLUTION FOR INJECTIONS FOR TREATING PROSTATE CANCER, RADIOPHARMACEUTICAL COMPOSITION BASED ON IT FOR TREATING PROSTATE CANCER AND METHOD FOR PREPARING RADIOPHARMACEUTICAL COMPOSITION | 2023 |
|
RU2817970C1 |
RADIOPHARMACEUTICAL FOR THE DIAGNOSIS OF PROSTATE CANCER BY POSITRON EMISSION TOMOGRAPHY AND METHOD FOR ITS PRODUCTION | 2022 |
|
RU2796106C1 |
PEPTIDE AGENT COMPRISING A PSMA-BINDING LIGAND BASED ON A UREA DERIVATIVE, A METHOD FOR PRODUCTION THEREOF AND USE THEREOF FOR PREPARING A CONJUGATE WITH A DRUG AND DIAGNOSTIC AGENT | 2018 |
|
RU2697519C1 |
PARAMINOHYPURIC ACID (PAH) AS A KIDNEY PROTECTOR | 2020 |
|
RU2804349C2 |
CONJUGATED BISPHOSPHONATES FOR DIAGNOSING AND TREATING BONE DISEASES | 2015 |
|
RU2742660C2 |
BOMBESIN ANALOGUE PEPTIDE ANTAGONIST CONJUGATES | 2009 |
|
RU2523531C2 |
Authors
Dates
2020-08-24—Published
2019-08-27—Filed