PREPARATION FOR MAGNETIC RESONANCE DIAGNOSTICS OF ONCOLOGICAL DISEASES CONTAINING DEUTERATED 3-O-METHYLGLUCOSE, AND DIAGNOSTIC METHOD USING SAID PREPARATION Russian patent published in 2020 - IPC A61K49/10 C07B59/00 

Abstract RU 2718052 C2

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to means for magnetic resonance diagnostics of oncological diseases. For this purpose, a diagnostic preparation and diagnostic method based on using a diagnostic preparation in form of 3-O-methylglucose containing deuterium bound with carbon in an amount greater than natural content or mixture of 3-O-methylglucose with different deuterium content. Method according to the invention involves magnetic resonance tomography and/or magnetic resonance spectroscopy on deuterium nuclei after the introduction of the diagnostic preparation after a time sufficient for accumulation of the diagnostic preparation in the tumor tissue of the subject, to obtain, respectively, MR-image and/or MR-spectrum.

EFFECT: group of inventions enables diagnosing oncologic diseases with high information value.

22 cl, 10 dwg, 4 ex

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RU 2 718 052 C2

Authors

Lesiv Aleksej Valerevich

Ivashkin Pavel Evgenevich

Gulyaev Mikhail Vladimirovich

Dorofeeva Evgeniya Olegovna

Kosenkov Aleksej Viktorovich

Kiselevskij Mikhail Valentinovich

Polshakov Vladimir Ivanovich

Dates

2020-03-30Published

2017-11-21Filed