METHODS OF TREATING HEPATITIS C Russian patent published in 2018 - IPC A61K31/4184 A61P31/12 

Abstract RU 2665365 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and is intended for the treatment of hepatitis C virus. Pan-genotypic HCV inhibitors are used, in particular methyl {(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5-(6-fluoro-2-{(2S)-1-N-(methoxycarbonyl)-O-methyl-L-threonyl]pyrrolidin-2-yl}-1H-benzimidazol-5-yl) pyrrolidin-2-yl)-6-fluoro-1H-benzimidazol-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl}carbamate together with an HCV protease inhibitor or HCV polymerase inhibitor. Patient is not genotyped for this treatment, the treatment lasts at least 24 weeks and does not include the administration of interferon.

EFFECT: group of inventions improves effectiveness of treatment.

13 cl, 3 tbl, 2 ex

Similar patents RU2665365C2

Title Year Author Number
METHODS FOR IMPROVING PHARMACOKINETICS 2010
  • Tren Dzhonatan K.
RU2591830C2
PANGENOTYPIC NS5A PROTEIN INHIBITOR OF HEPATITIS C VIRUS, A PHARMACEUTICAL COMPOSITION AND METHODS FOR PREPARING AND USING 2019
  • Ivashchenko Andrej Aleksandrovich
  • Ivashchenko Aleksandr Vasilevich
  • Mitkin Oleg Dmitrievich
RU2723482C1
ANTIVIRAL COMPOSITION AND METHOD OF ITS APPLICATION 2017
  • Aleksandr Vasilevich Ivashchenko
  • Mitkin Oleg Dmitrievich
RU2650610C1
BIS-BENZIMIDAZOLE DERIVATIVES AS HEPATITIS C VIRUS INHIBITORS 2010
  • Mak Gouen Dehvid
  • Demehn Samjuehl' Dominik
  • Last Stefan Zhjul'En
  • Vandik Koehn
  • Rabuasson P'Er Zhan-Mari Bernar
RU2540897C2
ALKYL [(S)-1-((S)-2-{5-[4-(4-{2-[(S)-1-((S)-2-METHOXYCARBONYLAMINO-3-METHYL-BUTYRYL)-PYRROLIDIN-2-YL]-3H-IMIDAZOL-4-YL}-BUTA-1,3-DIINYL)-PHENYL]-1H-IMIDAZOL-2-YL}-PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL]-CARBAMATE NAPHTHALENE-1,5-DISULPHONATE, PHARMACEUTICAL COMPOSITION, MEDICINAL AGENT, METHOD OF TREATING VIRAL DISEASES 2013
  • Ivashchenko Aleksandr Vasil'Evich
RU2507201C1
RESISTANT MUTANTS OF PROTEASE NS3-NS4A HCV 2004
  • Lin' Chao
  • Lin' Kaj
RU2365624C2
NUCLEOSIDE INHIBITORS OF RNA-POLYMERASE HCV NS5B, METHODS FOR PRODUCTION AND USE THEREOF 2014
  • Ivashchenko Aleksandr Vasil'Evich
RU2567854C1
PRODRUG OF POLYMERASE NS5B HCV INHIBITOR, METHOD FOR ITS PREPARATION AND APPLICATION 2017
  • Ivashchenko Aleksandr Vasilevich
  • Mitkin Oleg Dmitrievich
RU2644156C1
ANTIVIRAL COMPOUNDS 2009
  • Degoj Dehvid A.
  • Donner Pamela L.
  • Kati Uorren M.
  • Khatchins Charl'Z V.
  • Matulenko Mark A.
  • Dzhinkerson Tammi K.
  • Keddi Rajan Dzh.
RU2505540C2
PHENYLETHYNYL DERIVATIVES AS HEPATITIS C VIRUS INHIBITORS 2010
  • Mak Gouen Dehvid
  • Demehn Samjuehl' Dominik
  • Last Stefan Zhjul'En
  • Vandik Koehn
  • Rabuasson P'Er Zhan-Mari Bernar
RU2538507C2

RU 2 665 365 C2

Authors

Ng Tereza

Pajlot-Matias Tami Dzh.

Kati Uorren M.

Krishnan Preetkhi

Maring Klarens Dzh.

Mistri Neeta K.

Rejsh Tomas Dzh.

Vagner Rolf

Lyu Dachun

Pratt Dzhon K.

Matulenko Mark A.

Keddi Rajan Dzh.

Dates

2018-08-29Published

2013-09-17Filed