FIELD: chemistry.
SUBSTANCE: invention relates to particular compounds which are derivatives of 5-azaindazole, which are indicated in the claims. Said compounds are useful for inhibiting Pim kinase and for treating diseases such as cancer mediated by Pim kinase.
EFFECT: disclosed are methods of using compounds of formula (I) in vitro, in situ and in vivo to diagnose, prevent or treat similar diseases in mammalian cells or related pathological conditions.
6 cl, 4 tbl, 188 ex
Title | Year | Author | Number |
---|---|---|---|
SUBSTITUTED 2H-PYRAZOLE DERIVATIVE | 2016 |
|
RU2722363C2 |
USE OF 1H-PYRAZOLO[4,3-B]PYRIDINES AS PDE1 INHIBITORS | 2017 |
|
RU2759380C2 |
FURIN INHIBITORS | 2019 |
|
RU2799824C2 |
CHEMICAL COMPOUNDS 637: PYRIDOPYRIMIDINEDIONES AS PDE4 INHIBITORS | 2008 |
|
RU2479584C2 |
MORPHOLINE-PYRIDINE DERIVATIVES | 2015 |
|
RU2690154C2 |
NOVEL HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | 2019 |
|
RU2769507C1 |
COMPOSITIONS CONTAINING BENZOPIPERAZINE AS BROMODOMAIN BET INHIBITORS | 2014 |
|
RU2720237C2 |
COMPOUNDS OF PYRIDAZINAMIDE AND THEIR USE AS SYNTHETIC SYNECKINASIS INHIBITORS (SYK) | 2013 |
|
RU2627661C2 |
SUBSTITUTED 2-AMINOPYRIDINE PROTEIN KINASE INHIBITOR | 2014 |
|
RU2671212C2 |
PYRAZOLO [3,4-C] PYRIDINES AND METHODS OF APPLICATION THEREOF | 2012 |
|
RU2638116C2 |
Authors
Dates
2018-08-30—Published
2013-06-26—Filed