COMPOUNDS OF PYRIDAZINAMIDE AND THEIR USE AS SYNTHETIC SYNECKINASIS INHIBITORS (SYK) Russian patent published in 2017 - IPC C07D401/12 C07D237/24 C07D401/14 C07D405/12 C07D403/12 C07D471/04 A61K31/50 A61K31/501 A61P11/06 A61P29/00 A61P37/00 A61P35/00 

Abstract RU 2627661 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel pyridazinamides of the formula I , where all variable substituents are defined in the claims, and their pharmaceutically acceptable salts, as well as a pharmaceutical composition based on them.

EFFECT: compounds of the formula are SYK inhibitors and are useful for the treatment of autoimmune and inflammatory diseases.

10 cl, 1 tbl, 43 ex

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RU 2 627 661 C2

Authors

Germann Jokhannes Kornelius

Kennedi-Smit Dzhoshua

Lukas Metyu S.

Pedilla Fernando

Sot Majkl

Dates

2017-08-09Published

2013-01-07Filed