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2 665 630

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IPC

A61K36/77(2006-01-01)

A61K31/704(2006-01-01)

A61K131/00(2006-01-01)

A61P9/14(2006-01-01)

A61P13/08(2006-01-01)

(21) (22)

Application

2018106926, 2018-02-26

(24)

Start date

2018-02-26

(22)

Actual filing date

2018-02-26

(45)

Published

2018-09-03

(72)

Inventor

Azarkova Alina FedorovnaMeshkov Andrej IvanovichShejchenko Olga PetrovnaShejchenko Vladimir IvanovichIlin Mikhail MikhajlovichFedotcheva Tatyana AleksandrovnaShimanovskij Nikolaj Lvovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Vserossijskij Nauchno-Issledovatelskij Institut Lekarstvennykh I Aromaticheskikh Rastenij Vilar)

METHOD FOR PRODUCING DRY EXTRACT OF COMMON HORSE CHESTNUT SEEDS Russian patent published in 2018 - IPC A61K36/77 A61K31/704 A61K131/00 A61P9/14 A61P13/08

Abstract RU 2665630 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to the pharmaceutical industry, in particular to a method for the preparation of a standardized dry common horse chestnut seed extract (Fructus aesculi hippocastani). Method includes three-fold extraction of ground common horse chestnut seed in a feedstock: extractant ratio of 1:5 with constant stirring, distilling the obtained extract with butanol and twofold purification of the concentrated aqueous extract at a ratio of volumes of the aqueous and organic phases of 1:2, followed by its drying under certain conditions.

EFFECT: proposed method makes it possible to obtain a highly purified concentrated product with an increased content of the sum of triterpene glycosides.

1 cl, 1 tbl, 1 ex

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RU 2 665 630 C1

Authors

Azarkova Alina Fedorovna

Meshkov Andrej Ivanovich

Shejchenko Olga Petrovna

Shejchenko Vladimir Ivanovich

Ilin Mikhail Mikhajlovich

Fedotcheva Tatyana Aleksandrovna

Shimanovskij Nikolaj Lvovich

Dates

2018-09-03—Published

2018-02-26—Filed