INACTIVATED EMULSION VACCINE AGAINST FOOT-AND-MOUTH DISEASE TYPE A Russian patent published in 2018 - IPC A61K39/135 C12N7/00 

Abstract RU 2665850 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology. Invention is an inactivated emulsion vaccine against foot and mouth disease type A. Vaccine contains an avirulent and purified antigenic material from the strain of foot and mouth disease A virus No. 2269/VNIIZZh/2015 obtained in a suspension continuous cell line from the kidney of a newborn golden hamster (BHK-21/2-17). Antigenic material is a suspension containing mainly 146S immunogenic components of the foot and mouth disease virus. To produce an emulsion vaccine, use an oil adjuvant Montanide ISA-206 or Montanide ISA-70 in effective ratios.

EFFECT: vaccine possesses the high immunogeneicity and is able to provide the effective protection against the homologous agent of the infection persistent in Transcaucasus, Central Asia, Middle and Near East.

10 cl, 1 dwg, 9 tbl, 7 ex

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RU 2 665 850 C1

Authors

Lozovoj Dmitrij Anatolevich

Starikov Vyacheslav Alekseevich

Mikhalishin Dmitrij Valerevich

Doronin Maksim Igorevich

Borisov Aleksej Valerevich

Dates

2018-09-04Published

2017-12-25Filed