FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. Invention is an inactivated emulsion vaccine against foot and mouth disease type A. Vaccine contains an avirulent and purified antigenic material from the strain of foot and mouth disease A virus No. 2269/VNIIZZh/2015 obtained in a suspension continuous cell line from the kidney of a newborn golden hamster (BHK-21/2-17). Antigenic material is a suspension containing mainly 146S immunogenic components of the foot and mouth disease virus. To produce an emulsion vaccine, use an oil adjuvant Montanide ISA-206 or Montanide ISA-70 in effective ratios.
EFFECT: vaccine possesses the high immunogeneicity and is able to provide the effective protection against the homologous agent of the infection persistent in Transcaucasus, Central Asia, Middle and Near East.
10 cl, 1 dwg, 9 tbl, 7 ex
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Authors
Dates
2018-09-04—Published
2017-12-25—Filed