PLATINUM (IV) COMPLEXES WITH HIGH ANTITUMOR EFFICIENCY Russian patent published in 2018 - IPC C07F15/00 A61K31/282 A61K35/00 

Abstract RU 2666898 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a novel platinum (IV) complex with a "cis-trans-cis" configuration of ligands of formula (III): (III). Method for preparing a platinum complex and a pharmaceutical composition for treating a neoplastic disease comprising said complex are also provided.

EFFECT: platinum (IV) complex of formula (III) has excellent antitumor properties and low toxicity as compared to the prior art platinum complexes used or investigated.

8 cl, 3 tbl, 6 ex

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RU 2 666 898 C1

Authors

Kisilka Vladimir

Mengler Yan

Gavlovits Karel

Katser Petr

Tserveny Libor

Dates

2018-09-13Published

2014-09-03Filed