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2 667 906

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IPC

C07H19/23(2006-01-01)

A61K31/7056(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2017131729, 2017-09-11

(24)

Start date

2017-09-11

(22)

Actual filing date

2017-09-11

(45)

Published

2018-09-25

(72)

Inventor

Golubeva Irina SergeevnaEremina Vera AleksandrovnaMoiseeva Natalya IvanovnaEktova Lidiya VladimirovnaYavorskaya Nadezhda Petrovna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Tsentr Onkologii Imeni N.N. Blokhina" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Onkologii Im. N.N. Blokhina" Minzdrava Rossii)

DERIVATIVE OF THE CLASS OF N-GLYCOSIDES INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE - N-{12-(β-D-XYLOPYRANOSYL)-5,7-DIOXO-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOL-6-YL} PYRIDINE-2-CARBOXAMIDE, WHICH HAS CYTOTOXIC AND ANTITUMOR ACTIVITY Russian patent published in 2018 - IPC C07H19/23 A61K31/7056 A61P35/00

Abstract RU 2667906 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to use of the indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione N-glycoside derivative – N-{12-(β-D-xylopyranosyl)-5,7-dioxo-indolo[2,3-a]pyrrolo[3,4-c]carbazol-6-yl}pyridine-2-carboxamide as a compound having antitumor activity for the treatment of mice with adenocarcinoma of the mammary gland Ca 755, epidermoid carcinoma of Lewis lungs, melanoma B16, cervical cancer, adenocarcinoma of the colon ACTOL, Ehrlich tumor in therapeutic doses.

EFFECT: new application of a known biologically active compound has been proposed.

1 cl, 3 tbl, 1 ex

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RU 2 667 906 C1

Authors

Golubeva Irina Sergeevna

Eremina Vera Aleksandrovna

Moiseeva Natalya Ivanovna

Ektova Lidiya Vladimirovna

Yavorskaya Nadezhda Petrovna

Dates

2018-09-25—Published

2017-09-11—Filed