TUMOUR THERAPY AGENT Russian patent published in 2020 - IPC A61K31/7056 A61K47/10 A61K47/20 A61K47/32 A61P35/00 

Abstract RU 2726801 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to pharmaceutical industry and medicine, namely to an agent for tumour therapy, active against tumours of mice: lymphatic leukaemia P-388, Ehrlich tumours, Lewis lung epidermoid carcinoma, V-16 melanoma, cervical cancer cervix RShM-5, AKATOL intestinal cancer and adenocarcinoma Ca 755. Proposed agent contains (wt. %): 1.2 % n-{12-(β-d-xylopyranosyl)-5,7-dioxo-indolo[2,3-a]pyrrolo[3,4-c]carbazol-6-yl}pyridine-2-carboxamide; 13.0 % dimethylsulphoxide (DMSO); 47.4 % of Solidone 17PF, 38.4 % of ethyl alcohol (95 %).

EFFECT: invention provides creating a new anticancer agent of precise dosing characterized by high cytostatic effect, good solubility and stability during storage.

1 cl, 7 tbl

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RU 2 726 801 C1

Authors

Dmitrieva Mariya Vyacheslavovna

Borisova Larisa Mikhajlovna

Kiseleva Marina Petrovna

Golubeva Irina Sergeevna

Ektova Lidiya Vladimirovna

Eremina Vera Aleksandrovna

Tikhonova Nadezhda Ivanovna

Orlova Olga Lvovna

Nikolaeva Lyudmila Leonidovna

Shprakh Zoya Sergeevna

Lantsova Anna Vladimirovna

Gusev Dmitrij Vasilevich

Ignateva Elena Vladimirovna

Oborotova Nataliya Aleksandrovna

Kulbachevskaya Nataliya Yurevna

Konyaeva Olga Ivanovna

Ermakova Nadezhda Pavlovna

Dates

2020-07-15Published

2019-10-16Filed