STABILISED LIQUID ENZYME COMPOSITIONS Russian patent published in 2018 - IPC C07K5/08 C07K5/10 C11D3/386 

FIELD: chemistry.

SUBSTANCE: invention relates to a liquid composition for stabilising subtilisin, comprising subtilisin and a peptide aldehyde of formula B²-B¹-B⁰-H, where H denotes hydrogen; B⁰ is residue of Tyr; B¹ represents one amino acid residue of Ala or Val; and B² represents one amino acid residue with an attached benzyloxycarbonyl group (Cbz), or B² represents two amino acid residues containing an acetyl (Ac) N-terminal protecting group; and wherein the molar ratio of peptide aldehyde to subtilisin ranges from at least 1:1 to less than 1000:1.

EFFECT: peptide aldehydes or ketone derivatives are particularly efficient for stabilizing subtilisin-type proteases in aqueous compositions such as liquid detergents, including peptide compounds with OH-substituted phenylalanine aldehyde as the C-terminal residue.

5 cl, 3 ex