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2 668 969

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IPC

C07D498/12(2006-01-01)

A61K31/5365(2006-01-01)

A61K31/537(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2017137650, 2017-10-28

(24)

Start date

2017-10-28

(22)

Actual filing date

2017-10-28

(45)

Published

2018-10-05

(72)

Inventor

Maslivets Andrej NikolaevichDmitriev Maksim ViktorovichBalandina Svetlana YurevnaMoroz Anna Andreevna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

10-BENZYL-3,4-DIBENZOYL-2'-OXO-1',2',10,10A-TETRAHYDROSPIRO[BENZO[4,5]IMIDAZO[2,1-B][1,3]OXAZINE-2,3'-PYRROLES] Russian patent published in 2018 - IPC C07D498/12 A61K31/5365 A61K31/537 A61P31/00

Abstract RU 2668969 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of 10-benzyl-3,4-dibenzoyl-2'-oxo-1',2',10,10a-tetrahydrospiro[benzo[4,5]imidazo[2,1-b][1,3]oxazine-2,3'-pyrrole] of the general formula in which R¹ = Ph; R² = Ph, R³ = CH₂Ph (a); R¹ = OEt; R² = Ph; R³ = 4-C₆H₄Cl (b), Ph (c); R¹ = Ph; R² = COOMe; R³ = 4-C₆H₄Me (d), 4-C₆H₄OMe (e), 4-C₆H₄Br (f).

EFFECT: new compounds with a pronounced antimicrobial activity have been obtained which can be used as starting materials for the synthesis of heterocyclic systems and in pharmacology as potential drugs with antimicrobial properties.

1 cl, 1 tbl, 3 ex

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RU 2 668 969 C1

Authors

Maslivets Andrej Nikolaevich

Dmitriev Maksim Viktorovich

Balandina Svetlana Yurevna

Moroz Anna Andreevna

Dates

2018-10-05—Published

2017-10-28—Filed