Show metadata Hide metadata

(19)

(11)

2 668 982

(13)

(51)

IPC

C07D471/08(2006-01-01)

A61K31/439(2006-01-01)

A61P25/28(2006-01-01)

(21) (22)

Application

2017135970, 2017-10-10

(24)

Start date

2017-10-10

(22)

Actual filing date

2017-10-10

(45)

Published

2018-10-05

(72)

Inventor

Myasoedov Nikolaj FedorovichNagaev Igor YulianovichShevchenko Konstantin ValerevichShevchenko Valerij PavlovichGrigorev Vladimir ViktorovichLavrov Mstislav IgorevichBondarenko Ekaterina ValerevnaKalashnikova Elena Evgenevna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Molekulyarnoj Genetiki Rossijskoj Akademii Nauk

TRITIATED 3,7-BIS(2,3-DIHYDRO-1-BENZOFURAN-5-YLCARBONYL)-1,5-DIMETHYL-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE Russian patent published in 2018 - IPC C07D471/08 A61K31/439 A61P25/28

Abstract RU 2668982 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to tritiated 3,7-bis(2,3-dihydro-1-benzofuran-5-ylcarbonyl)-1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one of the formula I.

(I).

EFFECT: expansion of the range of labeled analogs of physiologically active compounds, namely, 3,7-bis(2,3-dihydro-1-benzofuran-5-ylcarbonyl)-1,5-dimethyl-3,7-diazabicyclo[3_3_1]nonan-9-one, which can find its application in medicine for the treatment of Alzheimer's and other neurodegenerative diseases.

1 cl, 1 ex

Similar patents RU2668982C1

Title	Year	Author	Number
N,N'-SUBSTITUTED 3,7-DIAZABICYCLO[3.3.1]NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND USE THEREOF	2015		RU2613071C1
N,N'-SUBSTITUTED 3,7-DIAZABICYCLO[3,3,1]NONANES WITH PHARMACOLOGICAL EFFECT, PHARMACOLOGICAL COMPOSITIONS ON THEIR BASE, AND APPLICATION METHOD	2006	Bachurin Sergej Olegovich Grigor'Ev Vladimir Viktorovich Zefirov Nikolaj Serafimovich Lavrov Mstislav Igorevich Lapteva Vera Leonidovna Paljulin Vladimir Aleksandrovich	RU2333211C1
TRITIUM-LABELED ACYL-COENZYME A	2006	Shevchenko Valerij Pavlovich Mjasoedov Nikolaj Fedorovich Nagaev Igor' Julianovich Bezuglov Vladimir Vilenovich	RU2305104C1
UNIFORMLY TRITIUM-LABELED 4,4-DIFLUORO-N-{(1S)-3-[3-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3,2,1]OCT-8-YL]-1-PHENYLPROPYL}CYCLOHEXANE CARBODIIMIDE	2008	Shevchenko Valerij Pavlovich Mjasoedov Nikolaj Fedorovich Nagaev Igor' Julianovich	RU2368613C1
ALICYCLIC DERIVATIVES OF N,N'-SUBSTITUTED 3,7-DIAZABICYCLO[3,3,1]NONANES, HAVING PHARMACOLOGICAL ACTIVITY, AND MEDICINAL AGENTS ON THEIR BASIS	2011	Zefirov Nikolaj Serafimovich Paljulin Vladimir Aleksandrovich Lavrov Mstislav Igorevich Zapol'Skij Maksim Ehduardovich	RU2489436C2
CHLOROHEXIDINE HIGHLY LABELED WITH TRITIUM	2005	Shevchenko Valerij Pavlovich Mjasoedov Nikolaj Fedorovich Nagaev Igor' Julianovich	RU2309929C2
TRITIUM-LABELLED 3-[5-(2-FLUROPHENYL)-1,2,4-OXADIAZOL-3-YL]BENZOIC ACID	2009	Shevchenko Valerij Pavlovich Mjasoedov Nikolaj Fedorovich Nagaev Igor' Julianovich	RU2398770C1
UNIFORMLY TRITIUM-LABELLED PYRO-Glu-His-Pro-NH	2013	Mjasoedov Nikolaj Fedorovich Shevchenko Valerij Pavlovich Nagaev Igor' Julianovich Shevchenko Konstantin Valer'Evich	RU2513852C1
UNIFORMLY MARKED WITH TRITIUM TILOSIN	2008	Shevchenko Valerij Pavlovich Mjasoedov Nikolaj Fedorovich Nagaev Igor' Julianovich	RU2360896C1
2-AMINO-4-(β-HYDROXYETHYLAMINO)ANISOLE UNIFORMLY LABELED WITH TRITIUM	2005	Shevchenko Valerij Pavlovich Mjasoedov Nikolaj Fedorovich Nagaev Igor' Julianovich	RU2291142C1

RU 2 668 982 C1

Authors

Myasoedov Nikolaj Fedorovich

Nagaev Igor Yulianovich

Shevchenko Konstantin Valerevich

Shevchenko Valerij Pavlovich

Grigorev Vladimir Viktorovich

Lavrov Mstislav Igorevich

Bondarenko Ekaterina Valerevna

Kalashnikova Elena Evgenevna

Dates

2018-10-05—Published

2017-10-10—Filed