FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine, namely, to a method for producing biodegradable composite materials with an open porosity for the restoration of bone tissue, comprising impregnating a porous ceramic framework with a polymer, which is characterized in that the mixture of hydroxyapatite with sodium chloride added in an amount of 10–50 wt% is compressed, followed by sintering at 700–800 °C for 5 hours, are kept in distilled water until sodium chloride dissolves to form a porous ceramic frame with an open porosity that is further dried and impregnated with a solution of a lactide-glycolide copolymer with a molecular weight of 10–100 kDa while being sonicated.
EFFECT: method for producing biodegradable composite materials is proposed.
1 cl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
POROUS MICROSPHERES OF CALCIUM AND MAGNESIUM BIOPHOSPHATE WITH ADJUSTED PARTICLE SIZE FOR BONE TISSUE REGENERATION | 2012 |
|
RU2497548C1 |
METHOD OF OBTAINING POROUS POLYMER BIODEGRADABLE PRODUCTS FOR OSTEANAGENESIS | 2006 |
|
RU2327709C2 |
SURGICAL MATERIAL (VERSIONS) | 2010 |
|
RU2433836C1 |
METHOD FOR PRODUCING POROUS BIOCERAMIC WOLLASTONITE | 2020 |
|
RU2743834C1 |
BIOCOMPATIBLE BIODEGRADABLE SCAFFOLD BASED ON POLYMER COMPOSITE CONTAINING HYDROXYAPATITE NANOPARTICLES | 2019 |
|
RU2756551C2 |
BIOCOMPATIBLE BONE-SUBSTITUTING MATERIAL AND METHOD OF OBTAINING THEREOF | 2012 |
|
RU2494721C1 |
DRY MIXTURE BASED ON HYDROXYAPATITE FOR AQUEOUS SUSPENSIONS FOR COATING ON BONE IMPLANTS AND AQUEOUS SUSPENSION BASED ON IT | 2022 |
|
RU2797279C1 |
METHOD OF PRODUCING CATION-SUBSTITUTED TRICALCIUM PHOSPHATE | 2015 |
|
RU2607743C1 |
POROUS CARRIER APPLICATION | 2001 |
|
RU2283140C2 |
METHOD OF BIOACTIVE CHITOSAN-BASED COATING APPLICATION ON POLYMER POROUS STRUCTURES | 2015 |
|
RU2600652C1 |
Authors
Dates
2018-10-12—Published
2017-12-22—Filed