BIORESORBABLE COMPOSITE MATERIAL FOR BONE TISSUE RECONSTRUCTION Russian patent published in 2025 - IPC A61L27/14 A61L27/16 A61L27/20 A61L27/58 A61F2/28 

Abstract RU 2834481 C1

FIELD: chemistry.

SUBSTANCE: invention relates to polymer composite materials which can be used in medicine for bone tissue reconstruction, particularly in cranioplasty. Disclosed bioresorbable composite material for bone tissue reconstruction contains 50-60 wt.% of chitosan fibres and/or chitosan composite fibres containing 0.01-0.50 wt.% chitin nanofibrils, and a binder made from a thermoplastic bioresorbable polymer based on poly(L-lactide), has radiotranslucency, bending strength of 100-130 MPa, bending modulus of 7-9 GPa, bending deformation of 2-3%, wherein bioresorbable material is obtained by pressing at T=140 °C and prepreg pressure 2 MPa, which is obtained by calendering at temperature T=185 °C of plain weave fabric from chitosan fibres and/or composite chitosan fibres containing 0.01-0.50 wt.% of chitin nanofibrils, and films of poly(L-lactide) with thickness of 300 mcm, and consists of eight layers of fabric based on chitosan fibres and/or composite chitosan fibres containing 0.01-0.50 wt.% of chitin nanofibrils, and eight layers of poly(L-lactide) film.

EFFECT: said material is bioresorbable, has a low density of the composite material compared to metals, which provides the radiopacity of the implant based thereon; has physical and mechanical characteristics, such as bending strength, elasticity modulus, bending deformation, which are comparable with similar characteristics of cortical bone tissue.

1 cl, 7 dwg, 2 ex

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RU 2 834 481 C1

Authors

Yudin Vladimir Evgenevich

Dobrovolskaya Irina Petrovna

Vaganov Gleb Vyacheslavovich

Tagandurdyeva Nurdzhemal Akmuradovna

Dresvyanina Elena Nikolaevna

Dates

2025-02-11Published

2024-04-25Filed