METHOD FOR PREDICTING THE RISK OF PROGRESSION OF GLAUCOMA Russian patent published in 2018 - IPC A61B8/06 A61B5/145 A61B10/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to ophthalmology, and can be used to predict the risk of progression of glaucoma. Determine the velocity of the pulse wave (PWV) in the arteries of the upper and lower extremities, flow-dependent vasodilation (HDV) of the brachial artery in a sample with reactive hyperemia, the total antioxidant capacity of blood serum (AOS), the level of depression (Ud) on the depression scale AT. Beka. In this case, the speed of propagation of the pulse wave is determined with the help of sphygmomanometry. Regression value F is calculated using the mathematical formula: F = 0.152 + 1.053 × PWV_worse – 2.007 × HDV - 0.075 × AOC + 0.891 × Ud, where PWV_worse is the worst of the pulse wave velocity from the right and left sides. Then calculate the risk factor for the progression of glaucoma Krp:Krp = 1/(1 + e^(-F)), where e is a mathematical constant equal to 2.718. At a value of the risk factor for the progression of Krp≤0.5 predict a low risk of glaucoma progression. If the risk factor for progression is known, Krp>0.5 predict a high risk of glaucoma progression.

EFFECT: method provides data with high sensitivity and specificity for monitoring the patient's condition and determining the need for optimization of treatment tactics by calculating the regression value F using a mathematical formula.

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