FIELD: chemistry.
SUBSTANCE: invention relates to a process for the preparation of crystalline forms of temozolomide, which consists of the following steps: dissolving the temozolomide in dimethyl sulphoxide into which a second organic solvent is added for recrystallisation, whereby the crystalline forms of temozolomide are obtained, the second organic solvent being methanol, isopropanol, dichloromethane, ethyl acetate or ethylene glycol. Invention also relates to the crystalline form of temozolomide.
EFFECT: technical result: a new method for the preparation of crystalline forms of temozolomide, having high product yield and purity.
9 cl, 21 dwg, 22 tbl, 18 ex
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