NOVEL CRYSTALLINE FORMS OF SODIUM SALT OF (4-{4-[5-(6-TRIFLUOROMETHYL-PYRIDIN-3-YLAMINO)PYRIDIN-2-YL]PHENYL}CYCLOHEXYL) ACETIC ACID Russian patent published in 2017 - IPC C07D401/12 A61K31/415 A61P3/04 

Abstract RU 2612556 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a crystalline form of a sodium salt (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)pyridin-2-yl] phenyl} cyclohexyl) acetic acid of formula (II)

in form of Modification C, where said Modification C is characterised by x-ray powder diffraction pattern, including two, four or more 2θ values (±0.1 degree) (CuKα λ=1.5418 Å), selected from a group comprising values 5.9, 17.0, 19.6, 22.5, 23.6, 26.4, 26.8, 28.4 and 30.0, at temperature of approximately 22 °C.

EFFECT: can be used in treating or preventing a condition or disorder, associated with DGAT1 activity.

15 cl, 8 dwg, 33 tbl, 21 ex

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Authors

Dates

2017-03-09Published

2011-10-05Filed