FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a thionucleoside derivative of general formula, where [1]: 
, R1, R2 and R3 are as described in the formula of invention or salt thereof. Also, provided is a pharmaceutical composition for use in the treatment of tumors, containing an effective amount of the above-mentioned thionucleoside derivative or a salt thereof.
EFFECT: technical result is the provision of a thionucleoside derivative exhibiting an excellent effect of inhibiting the growth of gemcitabine-resistant cells, and a pharmaceutical composition containing it, exhibiting excellent drug efficacy against a tumor that has acquired resistance to gemcitabine.
7 cl, 55 ex, 24 tbl
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