FIELD: chemistry; pharmaceutics.
SUBSTANCE: group of inventions relates to chemistry and pharmaceutics, namely, to treating HIV infection. Disclosed is an adenosine derivative of formula (4-A), which has reverse transcriptase inhibitor activity in vivo, a pharmaceutical composition based thereon, as well as methods of treating and preventing HIV infection, involving administering an effective dose of an adenosine derivative of formula (4-A).
EFFECT: group of inventions can be used for effective treatment or prevention of HIV infection.
19 cl, 5 dwg, 4 tbl, 15 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS AND PRODUCTION THEREOF | 2016 |
|
RU2720811C2 |
| COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE | 2013 |
|
RU2654482C2 |
| SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS | 2011 |
|
RU2606514C2 |
| NEW PYRROLOPYRIMIDINE COMPOUND OR ITS SALT, PHARMACEUTICAL COMPOSITION CONTAINING IT, IN PARTICULAR, AGENT FOR PREVENTION AND / OR TREATMENT OF TUMORS AND SO ON, BASED ON INHIBITING INFLUENCE ON NAE | 2015 |
|
RU2658008C2 |
| SPLICEOSTATIN ANALOGS | 2013 |
|
RU2618523C2 |
| ANTITUMOUR EFFECT ENHANCER CONTAINING PYRROLOPYRIMIDINE COMPOUND | 2016 |
|
RU2710380C1 |
| COMPOUNDS AND COMPOSITIONS USED FOR TREATMENT OF NTRK-RELATED DISORDERS | 2016 |
|
RU2744974C2 |
| TLR7 AGONISTS | 2019 |
|
RU2817014C2 |
| MACROCYCLIZATION REACTIONS AND INTERMEDIATE COMPOUNDS AND OTHER FRAGMENTS SUITABLE FOR PREPARING ANALOGUES OF HALICHONDRIN B | 2014 |
|
RU2710545C2 |
| SECONDARY MANNOSIS FOR BACTERIAL INFECTIONS TREATMENT | 2013 |
|
RU2667060C2 |
