FIELD: chemistry.
SUBSTANCE: invention relates to compounds of formula (A) or pharmaceutically acceptable salts thereof, as well as to pharmaceutical compositions having sodium channel blocking activity based thereon and methods of treating diseases mediated by said activity.
.
EFFECT: obtaining novel compounds which can be used as sodium channel blockers, are suitable for use in promoting hydration of the mucosal surface and treatment of diseases, including cystic fibrosis, chronic obstructive pulmonary disease, etc.
48 cl, 6 tbl, 7 dwg
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