CRYSTAL HYDRATE 5-HYDROXY-1H-IMIDAZOL-4-CARBOXAMIDE AND PHARMACEUTICAL COMPOSITION ON ITS BASIS Russian patent published in 2018 - IPC C07D233/90 A61K31/4164 A61P35/00 

Abstract RU 2672560 C1

FIELD: chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, namely to the 5-hydroxy-1H-imidazole-4-carboxamide hydrate crystal, where the crystal has diffraction peaks at diffraction angles of 8.1, 12.6, 17.1, 19.3, 20.3 and 21.6°, which are represented as 2θ in the picture of powder x-ray diffraction. Invention also relates to a pharmaceutical composition on its basis.

EFFECT: new crystal of 5-hydroxy-1H-imidazole-4-carboxamide hydrate was obtained, which has excellent storage stability.

2 cl, 16 dwg, 8 tbl, 27 ex

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Authors

Fujimoto Taisuke

Hashimoto Tomohiro

Hayashi Katsuyuki

Tanaka Tomoyuki

Dates

2018-11-16Published

2012-09-28Filed