METHOD FOR OBTAINING A SUBSTANCE FROM THE GONAD MUSSELS OF MYTILUS GALLOPROVINCIALIS, WHICH HAS ANTITUMOR ACTIVITY Russian patent published in 2018 - IPC A61K35/618 A61P35/00 

Abstract RU 2674033 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to pharmaceutical industry, in particular to a method for preparation of a substance from gonad mussels Mytilus galloprovincialis, which possesses antitumor activity. Method of obtaining a substance from the gonad mussels of M. galloprovincialis, which possesses antitumor activity, consists of the fact that from the mussels of M. galloprovincialis, 4–5 stages of maturity on a five-point scale are distinguished by raw gonads, crude gonads are homogenized in a chloroform : ethanol mixture, centrifuged, the residue is washed with water from non-lipid impurities, the chloroform fraction is evaporated in vacuo, hexane and an aqueous alcohol are added to the resulting lipid residue, mixture is shaken in a separatory funnel, the hexane fraction is separated and the water-alcohol fraction is extracted with hexane, the hexane fractions are combined and evaporated in vacuo to constant weight, under certain conditions.

EFFECT: above-described method allows to increase the yield of the final substance.

1 cl, 2 ex

Similar patents RU2674033C1

Title Year Author Number
FUNCTIONAL FOOD PRODUCT FROM BLACK SEA MUSSEL MYTILUS GALLOPROVINCIALIS LAM. 2019
  • Nekhoroshev Mikhail Valentinovich
  • Bocharova Elena Anatolevna
RU2716058C1
METHOD FOR OBTAINING A FUNCTIONAL PRODUCT ENRICHED WITH FUCOXANTHINOL AND METHYLXANTHINE 2021
  • Kapranova Larisa Leonidovna
  • Ryabushko Vitalij Ivanovich
  • Kapranov Sergej Viktorovich
RU2774887C1
METHOD OF PRODUCING AN OIL COMPOSITION ENRICHED WITH POLYUNSATURATED FATTY ACIDS AND CAROTENOIDS OF MYTILUS GALLOPROVINCIALIS 2020
  • Kapranova Larisa Leonidovna
  • Nekhoroshev Mikhail Valentinovich
  • Ryabushko Vitalij Ivanovich
  • Kapranov Sergej Viktorovich
RU2743019C1
METHOD OF PRODUCING BIOLOGICALLY ACTIVE SUBSTANCES FROM THE BLACK SEA MUSSELS Mytilus galloprovincialis Lam 2014
  • Nikonova Larisa Leonidovna
  • Nekhoroshev Mikhail Valentinovich
RU2599834C2
METHOD OF PRODUCING A FUNCTIONAL PRODUCT FROM MYTILUS GALLOPROVINCIALIS MUSSELS 2020
  • Kapranova Larisa Leonidovna
  • Nekhoroshev Mikhail Valentinovich
  • Ryabushko Vitalij Ivanovich
  • Kapranov Sergej Viktorovich
RU2743060C1
METHOD FOR OBTAINING ALCOHOL EXTRACT FROM OYSTER CRASSOSTREA GIGAS 2021
  • Nekhoroshev Mikhail Valentinovich
  • Zheleznova Svetlana Nikolaevna
  • Kozintsev Aleksandr Fedorovich
  • Bobko Nikolaj Ivanovich
  • Kapranova Larisa Leonidovna
  • Kapranov Sergej Viktorovich
  • Ryabushko Vitalij Ivanovich
RU2778451C1
METHOD OF INTEGRATED SAND DOLLAR PROCESSING 2009
  • Gerasimenko Natal'Ja Ivanovna
  • Logvinov Stepan Viktorovich
  • Kozlovskaja Ehmma Pavlovna
RU2398590C1
METHOD FOR OBTAINING BIOLOGICALLY ACTIVE SUBSTANCE FROM OYSTER CRASSOSTREA GIGAS 2021
  • Kapranova Larisa Leonidovna
  • Kapranov Sergej Viktorovich
  • Bobko Nikolaj Ivanovich
  • Ryabushko Vitalij Ivanovich
  • Nekhoroshev Mikhail Valentinovich
RU2778480C1
METHOD FOR PRODUCING REPRODUCTIVE PRODUCTS OF MUSSELS MYTILUS GALLOPROVINCIALIS LAM 2017
  • Karavantseva Nadezhda Vladimirovna
  • Pospelova Natalya Valerievna
  • Bobko Nikolaj Ivanovich
  • Nekhoroshev Mikhail Valentinovich
RU2678122C1
METHOD OF PREPARING BIOLOGICALLY ACTIVE SUBSTANCES SHOWING HEPATOPROTECTIVE EFFECT 1996
  • Barannik V.L.
  • Burkova V.N.
  • Vengerovskij A.I.
  • Kurakolova E.A.
  • Saratikov A.S.
  • Moskvin V.P.
  • Chuchalin V.S.
RU2120288C1

RU 2 674 033 C1

Authors

Kapranova Larisa Leonidovna

Ryabushko Vitalij Ivanovich

Nekhoroshev Mikhail Valentinovich

Apryshko Galina Ivanovna

Dates

2018-12-04Published

2017-11-09Filed