METHOD FOR STABILISING CHLORPHENIRAMINE AND SALT THEREOF Russian patent published in 2018 - IPC A61K9/08 A61K31/33 A61K31/4402 A61P27/02 A61P37/08 B65D47/18 

FIELD: package and storage.

SUBSTANCE: group of inventions relates to the chemical and pharmaceutical industry and is an ophthalmic product, which is a container containing a liquid preparation in the form of eye drops, containing chlorpheniramine and/or a pharmaceutically acceptable salt thereof, characterised in that: said liquid preparation has pH from 7.0 to 9.0; the container includes: a container body for placing a liquid preparation; a spout having an outlet through which the preparation should be poured, placed in the container body; and a cap for closing the outlet; and at least one of the surface of the walls of the internal space of the spout and the surface of the walls of the cap facing the outlet contains a resin containing polybutylene terephthalate; as well as a method for stabilising a liquid preparation, containing chlorpheniramine and/or a pharmaceutically acceptable salt thereof and having pH from 7.0 to 9.0, comprising placing a liquid preparation containing chlorpheniramine and/or a pharmaceutically acceptable salt thereof in a container in which at least part of the area forming the inner wall of the container includes a resin containing polybutylene terephthalate.

EFFECT: group of inventions allows to develop a technique that ensures stable storage of a liquid preparation chlorpheniramine and/or salt thereof with the suppression of the adsorption of the preparation on the walls of the container.

13 cl, 6 dwg, 8 tbl, 5 ex